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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5F
All Species:
34.55
Human Site:
Y650
Identified Species:
76
UniProt:
Q9Y2H2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2H2
NP_055752.1
1132
128407
Y650
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
D
E
Chimpanzee
Pan troglodytes
XP_508074
1133
128517
Y650
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
D
E
Rhesus Macaque
Macaca mulatta
XP_001099262
1133
128209
Y650
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
D
E
Dog
Lupus familis
XP_535034
1137
128796
Y654
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDA1
1132
127590
Y650
L
L
S
N
A
A
Y
Y
V
A
Y
Y
D
D
E
Rat
Rattus norvegicus
Q9ES21
587
67020
A120
Q
D
N
K
T
F
L
A
M
L
N
H
V
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514944
750
86937
R283
F
L
V
A
L
I
S
R
R
S
R
H
R
A
G
Chicken
Gallus gallus
XP_421792
1126
127898
Y650
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
D
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8E7C5
1120
126036
Y650
L
L
S
N
S
A
Y
Y
V
A
Y
Y
D
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392092
1118
126657
Y648
I
L
T
R
D
S
Y
Y
V
A
D
Y
D
D
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789035
2077
234760
Y676
I
I
S
E
K
A
Y
Y
I
A
S
Y
D
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.8
N.A.
90.5
21.2
N.A.
62.1
82.9
N.A.
71.2
N.A.
N.A.
35.3
N.A.
26.6
Protein Similarity:
100
99.9
99.1
95
N.A.
94.5
33.8
N.A.
64.4
90.2
N.A.
82.8
N.A.
N.A.
53.6
N.A.
38.4
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
6.6
100
N.A.
93.3
N.A.
N.A.
53.3
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
20
100
N.A.
100
N.A.
N.A.
80
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
73
0
10
0
82
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
0
0
10
0
82
73
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
73
% E
% Phe:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
19
10
0
0
0
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
82
0
0
10
0
10
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
64
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
10
10
0
10
0
10
0
0
% R
% Ser:
0
0
73
0
55
10
10
0
0
10
10
0
0
0
10
% S
% Thr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
73
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
82
82
0
0
64
82
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _